Jackson Hole is the South Entrance to Yellowstone National Park and Jackson, Wyoming (56 miles) is the largest town in the Jackson Hole valley. Even though it's quite a drive to the South Entrance, you get an extra bonus National Park in between, Grand Teton National Park (12 miles). Jackson's airport (JAC) has the largest airport in the gateway communites. From Jackson take 191, 89, 26 to the South Entance.